RSD

Pathophysiology:

Trademark of RSD is allodynia and ongoing pain (typically out of proportion to the injury). The cause of the initial injury could be major, minor trauma or no trauma at all. But one theory suggested about why the ongoing spontaneous pain is the result of chronic maladaptive sensitization of wide dynamic range neurones in dorsal horn of the spinal cord (NOT a heightened sympathetic tone). But there is a connection between WDR neurones and sympathetic system.